Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 14/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 13/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854286 | 0.89 | AGTR1 (0.44) | AGTR1AGTR2ACHE | |
| SCHEMBL9854274 | 0.88 | AGTR1 (0.42) | AGTR1AGTR2ALDH1A1MAPT | |
| SCHEMBL9854323 | 0.86 | LTB4R2 (0.42) | AGTR1 | |
| SCHEMBL9854360 | 0.82 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9854242 | 0.78 | AGTR1 (0.46) | AGTR1AGTR2ACHE | |
| SCHEMBL9854296 | 0.76 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9854279 | 0.74 | LTB4R2 (0.46) | AGTR1 | |
| SCHEMBL9854272 | 0.74 | LTB4R2 (0.42) | AGTR1 | |
| SCHEMBL9854253 | 0.74 | AGTR1 (0.45) | AGTR1AGTR2ACHE | |
| SCHEMBL8884587 | 0.73 | AGTR1 (0.49) | AGTR1AGTR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |