Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 14/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854296 | 0.85 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8874016 | 0.85 | LTB4R2 (0.45) | AGTR1 | |
| SCHEMBL9854242 | 0.84 | AGTR1 (0.46) | AGTR1AGTR2ACHE | |
| SCHEMBL8873614 | 0.83 | LTB4R2 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9854360 | 0.80 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8872931 | 0.79 | ABL1 (0.37) | — | |
| SCHEMBL9854286 | 0.76 | AGTR1 (0.44) | AGTR1AGTR2ACHE | |
| SCHEMBL8872997 | 0.75 | LTB4R2 (0.45) | AGTR1 | |
| SCHEMBL9854329 | 0.74 | AGTR1 (0.42) | AGTR1AGTR2ACHE | |
| SCHEMBL9854274 | 0.74 | AGTR1 (0.42) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |