Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473809 | 1.00 | FKBP1A (0.40) | FKBP1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10473808 | 1.00 | FKBP1A (0.40) | FKBP1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8441308 | 0.85 | NR1H2 (0.44) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9602159 | 0.83 | MEN1 (0.40) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL15080547 | 0.83 | MEN1 (0.40) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10474267 | 0.83 | FKBP1A (0.35) | FKBP1AALDH1A1MAPT | |
| SCHEMBL10472084 | 0.83 | FKBP1A (0.35) | FKBP1AALDH1A1MAPT | |
| SCHEMBL9854227 | 0.83 | FKBP1A (0.35) | FKBP1AALDH1A1MAPT | |
| SCHEMBL9854229 | 0.83 | FKBP1A (0.35) | FKBP1AALDH1A1MAPT | |
| SCHEMBL9602272 | 0.82 | MEN1 (0.39) | FKBP1AMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405834-A2 | Tetrazole excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4968678-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1990-11-06 | — | — | US | disclosed |