Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472084 | 1.00 | FKBP1A (0.35) | FKBP1AELANECTSGMAPTIDH1 | |
| SCHEMBL10474267 | 1.00 | FKBP1A (0.35) | FKBP1AELANECTSGMAPTIDH1 | |
| SCHEMBL9854229 | 1.00 | FKBP1A (0.35) | FKBP1AELANECTSGMAPTIDH1 | |
| SCHEMBL9854288 | 0.89 | SIGMAR1 (0.30) | — | |
| SCHEMBL9854281 | 0.89 | SIGMAR1 (0.30) | — | |
| SCHEMBL9854292 | 0.89 | SIGMAR1 (0.30) | — | |
| SCHEMBL9854340 | 0.83 | FKBP1A (0.40) | FKBP1AMAPTALDH1A1 | |
| SCHEMBL10473808 | 0.83 | FKBP1A (0.40) | FKBP1AMAPTALDH1A1 | |
| SCHEMBL10473809 | 0.83 | FKBP1A (0.40) | FKBP1AMAPTALDH1A1 | |
| SCHEMBL9854219 | 0.79 | FKBP1A (0.34) | FKBP1AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405834-A2 | Tetrazole excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4968678-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1990-11-06 | — | — | US | disclosed |