Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19346638 | 0.84 | EPHX2 (0.52) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL10489340 | 0.84 | CYP1A2 (0.56) | CPA1CYP1A2 | |
| SCHEMBL10521821 | 0.79 | MMP8 (0.61) | EPHX2PPARGMMP8MEN1NPC1 | |
| Trifluoroacetic Acid SCHEMBL7345257 | 0.76 | EPHX2 (0.53) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL15479082 | 0.76 | PPARG (0.58) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL3504311 | 0.76 | EPHX2 (0.70) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL3184765 | 0.74 | PPARG (0.57) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL9854363 | 0.74 | CA2 (0.42) | KMT2AL3MBTL1POLBHSD17B10 | |
| SCHEMBL563663 | 0.74 | PPARG (0.53) | EPHX2PPARGMMP8MEN1NPC1 | |
| SCHEMBL7436656 | 0.73 | CYP1A2 (0.61) | EPHX2PPARGMMP8MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252736-B1 | PROCESS FOR PREPARING FLUORINE-CONTAINING CARBOXYLIC ACID ESTER | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-24 | — | — | EP | disclosed |
| EP-0252736-A2 | Process for preparing fluorine-containing carboxylic acid ester | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-01-13 | — | — | EP | disclosed |