Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826539 | 0.84 | KDM4E (0.55) | KDM4EMTNR1AMTNR1BALDH1A1F2 | |
| SCHEMBL10537503 | 0.81 | KDM4E (0.55) | KDM4EMTNR1AMTNR1BALDH1A1F2 | |
| SCHEMBL10501806 | 0.77 | KDM4E (0.51) | KDM4EMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL2567669 | 0.77 | KDM4E (0.51) | KDM4EMTNR1AMTNR1BALDH1A1F2 | |
| SCHEMBL23795398 | 0.77 | ALDH1A1 (0.51) | KDM4EMTNR1AMTNR1BALDH1A1HDAC8 | |
| SCHEMBL28989628 | 0.76 | KDM4E (0.47) | KDM4EMTNR1AMTNR1BALDH1A1F2 | |
| SCHEMBL36974 | 0.76 | KDM4E (0.68) | KDM4EMTNR1AMTNR1BALDH1A1F2 | |
| SCHEMBL819646 | 0.76 | KDM4E (0.68) | KDM4EMTNR1AMTNR1BALDH1A1F2 | |
| SCHEMBL28989634 | 0.75 | KDM4E (0.49) | KDM4EMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL553714 | 0.74 | KDM4E (0.57) | KDM4EMTNR1AMTNR1BALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418917-A2 | Monomers and polymers containing acetal and aldehyde groups | National Starch and Chemical Investment Holding Corporation (US) | 1991-03-27 | — | — | EP | disclosed |