Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 8/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744725 | 0.94 | THRA (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL9745178 | 0.94 | THRA (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL9745085 | 0.94 | THRA (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL9746547 | 0.94 | THRA (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL9745238 | 0.94 | THRA (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL9746993 | 0.94 | THRA (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL9557208 | 0.92 | RARB (0.46) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL7756476 | 0.90 | RARB (0.43) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL7754308 | 0.89 | RARB (0.43) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL9745469 | 0.89 | LMNA (0.52) | RARBNFKB1NFKB2RELANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445037-A2 | Liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1991-09-04 | — | — | EP | disclosed |