SCHEMBL9854491

SCHEMBL9854491

O=[N+]([O-])c1ccc(P(c2ccccc2)c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
LMNA P02545 1/20 0.65
L3MBTL1 Q9Y468 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
CRHBP P24387 1/20 0.55
ATM Q13315 1/20 0.55
CRHR2 Q13324 1/20 0.55
TLR9 Q9NR96 1/20 0.55
HPGD P15428 1/20 0.55
ALOX12 P18054 1/20 0.55
TDP1 Q9NUW8 2/20 0.55
CYP3A4 P08684 1/20 0.55
CES1 P23141 2/20 0.53
CES2 O00748 1/20 0.53
POLB P06746 2/20 0.48
MAPK1 P28482 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
ESR1 P03372 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15660584 1.00 ALDH1A1 (0.65) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL15657354 0.91 ALDH1A1 (0.56) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL134487 0.91 ALDH1A1 (0.56) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL7912739 0.85 TDP1 (0.67) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL5973940 0.83 CYP2C19 (0.51) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL11805023 0.83 CYP1A2 (0.51) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Nitrobenzene SCHEMBL7748458 0.83 ALDH1A1 (0.94) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Benzene SCHEMBL28311584 0.83 ALDH1A1 (0.82) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL27947992 0.82 ALDH1A1 (0.54) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL15232959 0.82 ALDH1A1 (0.48) ALDH1A1LMNAL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
EP-2735581-A1 COMPOSITION AND POLYMER Asahi Kasei Chemicals Corporation (JP) 2014-05-28 EP disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed
EP-0271145-B1 PROCESS FOR THE CARBONYLATION OF CONJUGATED DIENES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-08-21 EP disclosed
US-4824817-A Catalyst for the carbonylation of conjugated dienes SHELL OIL COMPANY (US) 1989-04-25 US disclosed
EP-0271145-A2 Process for the carbonylation of conjugated dienes SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-06-15 EP disclosed