SCHEMBL27947992

SCHEMBL27947992

NCP(c1ccccc1)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
LMNA P02545 1/20 0.54
LOXL2 Q9Y4K0 1/20 0.50
CRHBP P24387 3/20 0.47
CRHR2 Q13324 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ATM Q13315 1/20 0.47
TLR9 Q9NR96 1/20 0.47
HPGD P15428 1/20 0.47
ALOX12 P18054 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
PTPRF P10586 1/20 0.45
PTPN2 P17706 1/20 0.45
PTPN1 P18031 1/20 0.45
PTPN11 Q06124 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854491 0.82 ALDH1A1 (0.65) ALDH1A1LMNACRHBPCRHR2L3MBTL1
SCHEMBL15660584 0.82 ALDH1A1 (0.65) ALDH1A1LMNACRHBPCRHR2L3MBTL1
SCHEMBL2329641 0.79 CYP3A4 (0.45) LOXL2CYP1A2CYP2C19TDP1
SCHEMBL15659623 0.78 LOXL2 (0.48) ALDH1A1LMNALOXL2CYP1A2CYP2C19
SCHEMBL15659636 0.78 LOXL2 (0.48) ALDH1A1LMNALOXL2CYP2C19CES1
SCHEMBL27947994 0.77 ALDH1A1 (0.41) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Hydrochloric Acid SCHEMBL3640613 0.75 CYP3A4 (0.41) LOXL2CYP1A2CYP2C19TDP1
Nitrobenzene SCHEMBL7748458 0.75 ALDH1A1 (0.94) ALDH1A1LMNALOXL2CRHBPCRHR2
SCHEMBL15660659 0.75 LOXL2 (0.45) ALDH1A1LMNALOXL2CYP2C19CES1
SCHEMBL15657276 0.75 LOXL2 (0.45) ALDH1A1LMNALOXL2CYP2C19CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502315-A Composition and polymer ASAHI KASEI CHEMICALS CORP 2014-01-08 CN disclosed