Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854547 | 0.72 | AHR (0.43) | AHRL3MBTL1NPC1POLBRAB9A | |
| SCHEMBL5170454 | 0.70 | NPC1 (0.44) | L3MBTL1NPC1POLBRAB9AMAPT | |
| SCHEMBL6388502 | 0.69 | AHR (0.67) | AHRTTRSMN1; SMN2 | |
| SCHEMBL472763 | 0.68 | AHR (0.50) | AHRTTRSMN1; SMN2 | |
| SCHEMBL21055936 | 0.67 | AHR (0.48) | AHRNPC1RAB9ATTRMAPT | |
| SCHEMBL9854558 | 0.66 | MAOA (0.56) | L3MBTL1NPC1POLBRAB9AMAPT | |
| SCHEMBL24589131 | 0.66 | AHR (0.66) | AHRL3MBTL1NPC1RAB9ATTR | |
| SCHEMBL24589137 | 0.66 | AHR (0.56) | AHRNPC1RAB9ATTRMAPT | |
| SCHEMBL5608879 | 0.66 | AHR (0.50) | AHRNPC1RAB9ATTRMAPT | |
| SCHEMBL17264051 | 0.64 | AHR (0.50) | AHRL3MBTL1TTRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430881-A2 | Photochromic compounds, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1991-06-05 | — | — | EP | disclosed |