Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684492 | 0.89 | AHR (0.47) | AHRNPC1POLBRAB9AL3MBTL1 | |
| SCHEMBL5170454 | 0.83 | NPC1 (0.44) | NPC1POLBRAB9AL3MBTL1CYP3A4 | |
| SCHEMBL9854558 | 0.83 | MAOA (0.56) | NPC1POLBRAB9AL3MBTL1CYP3A4 | |
| SCHEMBL1824078 | 0.73 | AHR (0.46) | AHRNPC1RAB9ACYP3A4MAOA | |
| SCHEMBL9854553 | 0.72 | AHR (0.39) | AHRNPC1POLBRAB9AL3MBTL1 | |
| SCHEMBL24566937 | 0.71 | MEN1 (0.46) | NPC1POLBRAB9AL3MBTL1CYP1A2 | |
| SCHEMBL24566597 | 0.71 | GAA (0.50) | NPC1POLBRAB9AL3MBTL1MAOA | |
| SCHEMBL24399894 | 0.71 | L3MBTL1 (0.36) | AHRNPC1POLBRAB9AL3MBTL1 | |
| SCHEMBL6389676 | 0.69 | AHR (0.70) | AHRNPC1RAB9ACYP3A4MAOA | |
| SCHEMBL31488273 | 0.69 | AHR (0.70) | AHRNPC1RAB9ACYP3A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430881-A2 | Photochromic compounds, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1991-06-05 | — | — | EP | disclosed |