SCHEMBL9854623

SCHEMBL9854623

CCCCC(c1ccccc1O)c1ccc(OC)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.39
TYR P14679 2/20 0.39
ACHE P22303 2/20 0.39
TSHR P16473 2/20 0.37
CNR2 P34972 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TP53 P04637 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
IDO1 P14902 1/20 0.36
HPGDS O60760 1/20 0.36
CYP2C9 P11712 1/20 0.36
HIF1A Q16665 1/20 0.36
EP300 Q09472 1/20 0.36
KAT8 Q9H7Z6 1/20 0.36
CDC25B P30305 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854628 0.83 CAPN1 (0.38) BCHETYRACHECNR2MAPT
SCHEMBL8853304 0.81 TSHR (0.53) TSHRCNR2GABRA1GABRB2
SCHEMBL8828951 0.76 TSHR (0.52) TSHRCNR2GABRA1GABRB2MAPT
SCHEMBL19638755 0.75 GPR84 (0.59) CYP2C9GAAMAPT
SCHEMBL20520279 0.75 TSHR (0.50) TSHRGABRA1GABRB2EP300KAT8
SCHEMBL20520238 0.75 TSHR (0.50) TSHRGABRA1GABRB2EP300KAT8
SCHEMBL20520227 0.75 TSHR (0.50) TSHRGABRA1GABRB2EP300KAT8
SCHEMBL20520230 0.75 TSHR (0.50) TSHRGABRA1GABRB2EP300KAT8
SCHEMBL20520273 0.75 TSHR (0.50) TSHRGABRA1GABRB2EP300KAT8
SCHEMBL20520293 0.75 TSHR (0.50) TSHRGABRA1GABRB2EP300KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed