SCHEMBL9854628

SCHEMBL9854628

CCCCC(c1ccc(O)cc1)c1ccc(OC)c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.38
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
BCHE P06276 2/20 0.38
TYR P14679 2/20 0.38
ACHE P22303 2/20 0.38
PDE4D Q08499 1/20 0.38
ADRB3 P13945 1/20 0.37
ALDH1A1 P00352 1/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ADRB2 P07550 2/20 0.36
CNR2 P34972 1/20 0.36
F2 P00734 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854623 0.83 BCHE (0.39) BCHETYRACHEMAPTCNR2
SCHEMBL7517085 0.75 SIGMAR1 (0.50) ALDH1A1MAPTCNR2
SCHEMBL27703049 0.75 TSHR (0.44) ALDH1A1MAPTCNR2
SCHEMBL335067 0.73 ESR1 (0.50) ACHEADRB3ALDH1A1MAPTCNR2
SCHEMBL28981975 0.72 IMPDH2 (0.45) GLAMAPTNPSR1CNR2
Propane SCHEMBL28335023 0.72 ESR1 (0.48) ACHEADRB3ALDH1A1MAPTCNR2
SCHEMBL19638755 0.72 GPR84 (0.59) ALDH1A1MAPTNPSR1
SCHEMBL27460165 0.71 SIGMAR1 (0.53) ACHEADRB3ALDH1A1MAPTCNR2
SCHEMBL11291735 0.71 PDE4D (0.59) PDE4DALDH1A1MAPT
SCHEMBL8352515 0.70 ESR1 (0.47) ACHEADRB3ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed