SCHEMBL9854638

SCHEMBL9854638

CCCC1c2ccccc2OC(=O)Oc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GRM8 O00222 3/20 0.43
GRM7 Q14831 3/20 0.43
USP2 O75604 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAPT P10636 1/20 0.41
GRM1 Q13255 2/20 0.39
GRM4 Q14833 2/20 0.39
GRM2 Q14416 2/20 0.39
GRM3 Q14832 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11994168 0.89 CYP1A2 (0.50) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL10481361 0.86 KMT2A (0.44) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL10690124 0.85 KMT2A (0.45) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL28633848 0.78 KMT2A (0.50) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL6125509 0.76 KMT2A (0.51) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL4592036 0.76 KMT2A (0.46) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL21436988 0.75 GRM8 (0.51) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL10692504 0.75 MAOA (0.45) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL480910 0.75 KMT2A (0.47) KMT2AMEN1TSHRSMN1; SMN2NPSR1
SCHEMBL17875264 0.74 KMT2A (0.45) KMT2AMEN1TSHRSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed