Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978813 | 0.83 | ALDH1A1 (0.55) | LTB4R2ALDH1A1TSHRTP53 | |
| SCHEMBL31319816 | 0.81 | CA2 (0.42) | HSD17B3LTB4R2ESR1ESR2ALDH1A1 | |
| SCHEMBL9298794 | 0.81 | KDM4A (0.42) | HSD17B3ESR1ESR2 | |
| SCHEMBL10723360 | 0.79 | ALDH1A1 (0.51) | ESR1ESR2ALDH1A1HSD17B10 | |
| SCHEMBL3177450 | 0.79 | HSD17B3 (0.57) | HSD17B3LTB4R2ESR1ESR2ALDH1A1 | |
| SCHEMBL2984167 | 0.78 | NPC1 (0.53) | LTB4R2ALDH1A1TP53 | |
| SCHEMBL18240146 | 0.76 | NPC1 (0.54) | LTB4R2ALDH1A1TSHRTP53 | |
| SCHEMBL12472589 | 0.76 | NPC1 (0.54) | LTB4R2ALDH1A1TSHRTP53 | |
| SCHEMBL18240156 | 0.76 | NPC1 (0.54) | LTB4R2ALDH1A1TSHRTP53 | |
| SCHEMBL7643097 | 0.76 | NPC1 (0.54) | LTB4R2ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406640-A2 | Thermoplastic polycarbonate compositions having improved oxygen barrier properties | GENERAL ELECTRIC COMPANY (US) | 1991-01-09 | — | — | EP | disclosed |