Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22382257 | 0.84 | ABCB1 (0.51) | ABCB1TAAR1HTR1ADRD2ABCG2 | |
| SCHEMBL8073005 | 0.83 | L3MBTL1 (0.51) | ALDH1A1HTR1ADRD2 | |
| SCHEMBL30136331 | 0.82 | TAAR1 (0.58) | ABCB1TAAR1ALDH1A1KCNH2 | |
| SCHEMBL8062343 | 0.82 | TAAR1 (0.58) | ABCB1TAAR1ALDH1A1KCNH2 | |
| SCHEMBL22700920 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HTR1ADRD2 | |
| SCHEMBL8070949 | 0.80 | MAPT (0.45) | KDM4EALDH1A1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL8072069 | 0.79 | CYP1A2 (0.49) | KDM4EALDH1A1 | |
| SCHEMBL28575949 | 0.78 | HRH1 (0.44) | TAAR1KDM4EBCHEHTR1ADRD2 | |
| SCHEMBL16499824 | 0.77 | TAAR1 (0.67) | ABCB1TAAR1 | |
| SCHEMBL27761600 | 0.77 | TAAR1 (0.43) | ABCB1TAAR1ALDH1A1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424959-A2 | Organosilylalkyl-aromatic compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1991-05-02 | — | — | EP | disclosed |