Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079979 | 0.83 | L3MBTL1 (0.56) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL15079868 | 0.82 | CYP1A2 (0.53) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL15079870 | 0.79 | CYP1A2 (0.50) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL15079866 | 0.77 | L3MBTL1 (0.53) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL15080038 | 0.77 | CYP1A2 (0.49) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL9854722 | 0.77 | MPO (0.51) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL15079864 | 0.76 | L3MBTL1 (0.49) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL9854753 | 0.76 | L3MBTL1 (0.45) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL15080035 | 0.75 | MAOB (0.51) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL11705264 | 0.74 | HRH1 (0.56) | RAB9ANPC1DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428423-A2 | Aryloxy alkyl benzenes, processes for their preparation and pharmaceutical compositions containing them | LIPHA S.A. (FR) | 1991-05-22 | — | — | EP | disclosed |