Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388904 | 0.93 | GRIN2B (0.47) | GRIN2B | |
| SCHEMBL2002532 | 0.91 | GRIN2B (0.46) | GRIN2B | |
| SCHEMBL18167359 | 0.84 | GRIN2B (0.45) | GRIN2B | |
| SCHEMBL1378380 | 0.83 | GRIN2B (0.43) | GRIN2B | |
| SCHEMBL19553769 | 0.80 | METAP2 (0.43) | GRIN2B | |
| SCHEMBL1375990 | 0.78 | METAP2 (0.41) | GRIN2B | |
| SCHEMBL2951836 | 0.78 | NPC1 (0.41) | GRIN2B | |
| SCHEMBL10600439 | 0.76 | NPC1 (0.43) | GRIN2B | |
| SCHEMBL12921851 | 0.75 | PARP1 (0.49) | GRIN2B | |
| SCHEMBL4373720 | 0.73 | PARP1 (0.43) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433898-A2 | Analogs of oxetanyl purines and pyrimidines | ABBOTT LABORATORIES (US) | 1991-06-26 | — | — | EP | disclosed |