Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002532 | 0.96 | GRIN2B (0.46) | GRIN2B | |
| SCHEMBL9854786 | 0.93 | GRIN2B (0.49) | GRIN2B | |
| SCHEMBL18167359 | 0.81 | GRIN2B (0.45) | GRIN2B | |
| SCHEMBL1378380 | 0.79 | GRIN2B (0.43) | GRIN2B | |
| SCHEMBL2951836 | 0.77 | NPC1 (0.41) | GRIN2B | |
| SCHEMBL1375990 | 0.77 | METAP2 (0.41) | GRIN2B | |
| SCHEMBL4156178 | 0.77 | IRAK4 (0.32) | GRIN2B | |
| SCHEMBL19553769 | 0.77 | METAP2 (0.43) | GRIN2B | |
| SCHEMBL10600439 | 0.76 | NPC1 (0.43) | GRIN2B | |
| Hydrochloric Acid SCHEMBL6821628 | 0.76 | KDM4E (0.42) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774084-B2 | Adenine derivatives and their use as UV-photoprotective agents | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2020-09-15 | — | — | US | disclosed |
| US-10662194-B2 | Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2020-05-26 | — | — | US | disclosed |
| EP-3233860-B1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIV PALACKEHO (CZ) | 2020-01-29 | — | — | EP | disclosed |
| US-20180298004-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2018-10-18 | — | — | US | disclosed |
| EP-3341371-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | Univerzita Palackého V Olomouci (CZ) | 2018-07-04 | — | — | EP | disclosed |
| US-20170342072-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2017-11-30 | — | — | US | disclosed |
| WO-2017036434-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2017-03-09 | — | — | WO | disclosed |
| US-20130072505-A1 | 6,9-Disubstituted Purine Derivatives and Their Use for Treating Skin | SZUCOVA LUCIE (CZ) | 2013-03-21 | — | — | US | disclosed |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | SZUCOVA LUCIE | 2011-09-15 | — | — | US | disclosed |
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | SZUCOVA LUCIE | 2010-09-16 | — | — | US | disclosed |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180298004-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | XPA, ERCC4, UNG | GRIN2B 4700/4885 |
| US-20100234401-A1 | 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin | UNG, P2RY6, MPG | GRIN2B 4767/4885 |
| US-10662194-B2 | Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress | TPMT, MTAP, ATIC | GRIN2B 3398/4885 |
| US-20110224238-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin | UNG, P2RY6, MPG | GRIN2B 4767/4885 |
| US-20170342072-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | TPMT, MTAP, ATIC | GRIN2B 3398/4885 |
| US-20130072505-A1 | 6,9-Disubstituted Purine Derivatives and Their Use for Treating Skin | UNG, P2RY6, MPG | GRIN2B 4767/4885 |
| US-20080009508-A1 | 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin | UNG, P2RY6, MPG | GRIN2B 4767/4885 |
| US-10774084-B2 | Adenine derivatives and their use as UV-photoprotective agents | XPA, ERCC4, UNG | GRIN2B 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.