Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9155909 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1MAPTLMNAHDAC3 | |
| SCHEMBL9150862 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1MAPTLMNACA1 | |
| SCHEMBL10792509 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1MAPTLMNAHTT | |
| SCHEMBL10796427 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1MAPTLMNAHTT | |
| SCHEMBL7371177 | 0.76 | TRPV1 (0.60) | SMN1; SMN2L3MBTL1MAPTLMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL4187499 | 0.75 | TRPV1 (0.59) | SMN1; SMN2L3MBTL1MAPTLMNAHSD17B10 | |
| SCHEMBL9156183 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1MAPTLMNACA1 | |
| Ammonia Solution, Strong SCHEMBL9151824 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2L3MBTL1MAPTLMNACA1 | |
| SCHEMBL7367758 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1MAPTLMNAHDAC3 | |
| SCHEMBL10601679 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430336-A2 | Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives | ZAMBON GROUP S.p.A. (IT) | 1991-06-05 | — | — | EP | disclosed |