Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156183 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| Ammonia Solution, Strong SCHEMBL9155909 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL10792509 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL9854819 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL7371177 | 0.83 | TRPV1 (0.60) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL4187499 | 0.82 | TRPV1 (0.59) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| Ammonia Solution, Strong SCHEMBL9151824 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL7367758 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL10601679 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL7370487 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2CA1CA2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430336-B1 | Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives | ZAMBON SPA (IT) | 1995-02-15 | — | — | EP | disclosed |
| US-5138084-A | PROCESS FOR THE PREPARATION OF 4-O-PHOSPHATES OF DOPAMINE AND DOPAMINE DERIVATIVES | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1992-08-11 | — | — | US | disclosed |
| EP-0430336-A2 | Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives | ZAMBON GROUP S.p.A. (IT) | 1991-06-05 | — | — | EP | disclosed |