Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602965 | 0.95 | SLC2A1 (0.47) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL10793664 | 0.95 | MTNR1A (0.48) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL10600778 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL10796427 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL9150862 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL9156183 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL7369120 | 0.78 | HDAC1 (0.41) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4187817 | 0.78 | TRPV1 (0.55) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL2851561 | 0.78 | LMNA (0.61) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| Benzyl Phenethylcarbamate SCHEMBL4287199 | 0.77 | LMNA (0.73) | SMN1; SMN2LMNAHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438047-A | Diphosphates of catecholamines and pharmaceutical compositions containing them | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | disclosed |
| EP-0607394-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994003461-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.P.A. (IT) | 1994-02-17 | — | — | WO | disclosed |