Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20342093 | 0.79 | — | — | |
| SCHEMBL27975846 | 0.75 | — | — | |
| SCHEMBL873517 | 0.74 | NAMPT (0.40) | NAMPTIMPDH2ACACB | |
| SCHEMBL27873946 | 0.73 | — | — | |
| SCHEMBL6274565 | 0.70 | NAMPT (0.36) | NAMPT | |
| SCHEMBL5960490 | 0.70 | LMNA (0.32) | NAMPT | |
| SCHEMBL28212014 | 0.68 | CYP3A4 (0.43) | NAMPTIMPDH2IMPDH1ACACB | |
| SCHEMBL4888168 | 0.68 | ALDH1A1 (0.38) | NAMPTACACB | |
| SCHEMBL18475140 | 0.67 | NAMPT (0.46) | NAMPT | |
| SCHEMBL2625480 | 0.67 | CHRNA4 (0.39) | IMPDH2IMPDH1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409418-A1 | Heterocyclic tertiary alcohols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |