Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855275 | 0.83 | MAPT (0.43) | EPHX2PPARGMAPTKMT2ALMNA | |
| SCHEMBL10983101 | 0.81 | CHRM2 (0.43) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL9855552 | 0.81 | MAPT (0.42) | EPHX2PPARGMAPTKMT2ALMNA | |
| SCHEMBL9622043 | 0.80 | MAPT (0.41) | EPHX2PPARGMAPTKMT2ALMNA | |
| SCHEMBL9855217 | 0.80 | MAPT (0.41) | EPHX2PPARGMAPTKMT2ALMNA | |
| SCHEMBL10977789 | 0.79 | KIF11 (0.46) | EPHX2MAPTKMT2ALMNAMEN1 | |
| SCHEMBL9855979 | 0.78 | MAPT (0.39) | EPHX2PPARGMAPTKMT2ALMNA | |
| SCHEMBL29571281 | 0.75 | EPHX2 (0.43) | EPHX2PPARGMAPTKMT2ALMNA | |
| SCHEMBL10984423 | 0.74 | L3MBTL1 (0.58) | PPARGMAPTKMT2ALMNAMEN1 | |
| SCHEMBL8253229 | 0.74 | MAPT (0.44) | EPHX2PPARGMAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |