Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618246 | 0.91 | ALDH1A1 (0.38) | MAPTHTTALDH1A1CRHBPCRHR2 | |
| SCHEMBL3877302 | 0.88 | ALDH1A1 (0.37) | MAPTHTTALDH1A1NPSR1POLB | |
| SCHEMBL9842282 | 0.87 | ALDH1A1 (0.36) | MAPTHTTALDH1A1NPSR1POLB | |
| SCHEMBL10801759 | 0.79 | MAPT (0.35) | MAPTALDH1A1NPSR1POLBNPC1 | |
| SCHEMBL10804700 | 0.78 | PLAUR (0.37) | MAPTHTTALDH1A1RAB9AKMT2A | |
| SCHEMBL9848550 | 0.77 | POLB (0.36) | MAPTHTTALDH1A1CRHBPCRHR2 | |
| SCHEMBL548194 | 0.74 | CYP2C9 (0.36) | MAPTHTTALDH1A1NPSR1RAB9A | |
| SCHEMBL4750113 | 0.74 | ALDH1A1 (0.36) | MAPTHTTALDH1A1KMT2ACYP3A4 | |
| SCHEMBL339448 | 0.73 | TLR8 (0.36) | ALDH1A1RAB9AKMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL10587427 | 0.72 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2C9HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414229-A2 | Heat-sensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| EP-0234540-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-09-02 | — | — | EP | disclosed |