Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855024 | 0.91 | APP (0.59) | APPKCNH2MCHR1GRM5PDE10A | |
| SCHEMBL9856015 | 0.83 | NQO1 (0.45) | ACACB | |
| SCHEMBL9855654 | 0.81 | APP (0.49) | APPKCNH2MCHR1GRM5PDE10A | |
| SCHEMBL9855090 | 0.81 | ACACB (0.46) | MCHR1ACACB | |
| SCHEMBL9855591 | 0.81 | ACACB (0.45) | MCHR1ACACB | |
| SCHEMBL9855728 | 0.79 | APP (0.46) | APPKCNH2MCHR1GRM5HAO1 | |
| SCHEMBL10300057 | 0.77 | APP (0.77) | APPKCNH2MCHR1CA12CA1 | |
| SCHEMBL674764 | 0.77 | APP (0.77) | APPKCNH2MCHR1CA12CA1 | |
| SCHEMBL9855292 | 0.76 | APP (0.44) | APPKCNH2MCHR1GRM5HAO1 | |
| SCHEMBL9496175 | 0.75 | MCHR1 (0.57) | APPKCNH2MCHR1GRM5ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |