Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855090 | 0.94 | ACACB (0.46) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9855378 | 0.92 | ACACB (0.49) | ACACBMCHR1CACNA2D1CHRNB2CHRNB4 | |
| SCHEMBL9856015 | 0.88 | NQO1 (0.45) | ACACBCACNA2D1 | |
| SCHEMBL9855368 | 0.85 | ACACB (0.51) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9855145 | 0.84 | MCHR1 (0.46) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9855813 | 0.84 | ACACB (0.44) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9854953 | 0.83 | NR5A1 (0.50) | ACACBMCHR1LTA4H | |
| SCHEMBL9855520 | 0.82 | ACACB (0.44) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10509708 | 0.81 | ACACB (0.36) | ACACBMCHR1 | |
| SCHEMBL9855671 | 0.81 | APP (0.50) | ACACBMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |