Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498836 | 1.00 | FFAR1 (0.39) | FFAR1HRH3HRH2HRH1ALDH1A1 | |
| SCHEMBL9498830 | 1.00 | FFAR1 (0.39) | FFAR1HRH3HRH2HRH1ALDH1A1 | |
| SCHEMBL10513499 | 0.90 | FFAR1 (0.36) | FFAR1HRH3HRH2HRH1ALDH1A1 | |
| SCHEMBL9497535 | 0.90 | HRH3 (0.45) | FFAR1HRH3HRH2HRH1HSD11B1 | |
| SCHEMBL9497527 | 0.90 | HRH3 (0.45) | FFAR1HRH3HRH2HRH1HSD11B1 | |
| SCHEMBL21258030 | 0.86 | FFAR1 (0.47) | FFAR1HRH3ALDH1A1CYP2A6FFAR4 | |
| SCHEMBL23960274 | 0.83 | ALDH1A1 (0.36) | FFAR1ALDH1A1FFAR4 | |
| SCHEMBL9495017 | 0.83 | FFAR1 (0.39) | FFAR1HRH3ALDH1A1CYP2A6FFAR4 | |
| SCHEMBL9855349 | 0.83 | FFAR1 (0.39) | FFAR1HRH3ALDH1A1CYP2A6FFAR4 | |
| SCHEMBL9495022 | 0.83 | FFAR1 (0.39) | FFAR1HRH3ALDH1A1CYP2A6FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |