Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509821 | 0.95 | DRD3 (0.40) | DRD3DRD2DRD4TSHRHSD17B10 | |
| SCHEMBL9854840 | 0.93 | DRD3 (0.42) | DRD3DRD2DRD4TSHRHSD17B10 | |
| SCHEMBL9854898 | 0.91 | TSHR (0.43) | DRD3DRD2DRD4TSHRHSD17B10 | |
| SCHEMBL9855708 | 0.90 | TSHR (0.45) | DRD3DRD2DRD4TSHRHSD17B10 | |
| SCHEMBL9855604 | 0.90 | DRD3 (0.42) | DRD3DRD2DRD4TSHRHSD17B10 | |
| SCHEMBL9855525 | 0.87 | DRD2 (0.43) | DRD3DRD2DRD4KDM1A | |
| SCHEMBL9855214 | 0.87 | DRD2 (0.43) | DRD3DRD2DRD4KDM1A | |
| SCHEMBL9855021 | 0.87 | DRD3 (0.40) | DRD3DRD2DRD4TSHRHSD17B10 | |
| SCHEMBL11355219 | 0.87 | ESR2 (0.43) | DRD3TSHRHSD17B10HRH3HRH2 | |
| SCHEMBL9854835 | 0.86 | KDM1A (0.41) | DRD3DRD2DRD4KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |