Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.45 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.41 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855954 | 0.84 | MEN1 (0.43) | KMT2AMEN1TSHRRARBSPHK1 | |
| SCHEMBL2636679 | 0.83 | KMT2A (0.88) | KMT2AMEN1TSHRTP53PLA2G4B | |
| SCHEMBL9855784 | 0.77 | S1PR5 (0.43) | TSHRTP53PLA2G4B | |
| SCHEMBL9648524 | 0.76 | S1PR5 (0.41) | KMT2ATSHRTP53PLA2G4B | |
| SCHEMBL9648515 | 0.76 | S1PR5 (0.41) | KMT2ATSHRTP53PLA2G4B | |
| SCHEMBL9646244 | 0.76 | S1PR5 (0.41) | KMT2ATSHRTP53PLA2G4B | |
| SCHEMBL9648505 | 0.76 | S1PR5 (0.41) | KMT2ATSHRTP53PLA2G4B | |
| SCHEMBL9646236 | 0.76 | S1PR5 (0.41) | KMT2ATSHRTP53PLA2G4B | |
| SCHEMBL9646227 | 0.76 | S1PR5 (0.41) | KMT2ATSHRTP53PLA2G4B | |
| SCHEMBL9436215 | 0.75 | TP53 (0.46) | TSHRTP53PLA2G4BRARBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075032-A | Electrooptics, switches, displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-12-24 | — | — | US | disclosed |
| US-4886620-A | Smectic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-12-12 | — | — | US | disclosed |