Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5621969 | 0.82 | GAA (0.82) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL9045649 | 0.82 | GAA (0.82) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL24011910 | 0.80 | GAA (0.78) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL9123832 | 0.80 | GAA (0.78) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL2637278 | 0.80 | GAA (0.95) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL5669332 | 0.79 | MAPT (0.57) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL25433146 | 0.78 | CYP2D6 (0.50) | LMNAMAPTDRD2DRD4DRD3 | |
| SCHEMBL29434581 | 0.76 | GAA (0.72) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL9152183 | 0.76 | GAA (0.72) | GAAJAK2LMNAMAPTDRD2 | |
| SCHEMBL2349415 | 0.76 | GAA (0.72) | GAAJAK2LMNAMAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |