SCHEMBL5669332

SCHEMBL5669332

C#CCOc1ccccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
GAA P10253 2/20 0.57
JAK2 O60674 1/20 0.57
LMNA P02545 1/20 0.57
MAOB P27338 2/20 0.47
APP P05067 1/20 0.46
TSHR P16473 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
TP53 P04637 1/20 0.45
HPGD P15428 2/20 0.44
CYP3A4 P08684 1/20 0.42
CYP2A6 P11509 1/20 0.42
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
DRD3 P35462 1/20 0.42
NPC1 O15118 2/20 0.41
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30663731 0.84 MAPT (0.56) MAPTMAOBTSHRCA2HPGD
SCHEMBL10347560 0.84 MAPT (0.56) MAPTMAOBTSHRCA2HPGD
Hydrochloric Acid SCHEMBL21694039 0.82 MAPT (0.55) MAPTMAOBTSHRCA2HPGD
SCHEMBL20530571 0.81 CYP3A4 (0.49) MAPTGAAJAK2MAOBCYP3A4
SCHEMBL20530587 0.80 MAOB (0.42) MAPTGAAJAK2LMNAMAOB
SCHEMBL18335399 0.80 CYP3A4 (0.41) MAPTGAAJAK2LMNAMAOB
SCHEMBL10808553 0.79 GAA (0.57) MAPTGAAJAK2LMNAAPP
SCHEMBL11873912 0.79 GAA (0.57) MAPTGAAJAK2LMNAAPP
SCHEMBL9855809 0.79 GAA (0.62) MAPTGAAJAK2LMNAAPP
SCHEMBL26013294 0.78 MAOB (0.64) MAPTMAOBCA2CYP3A4CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1200431-B3 QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTORS LIGANDS ALMIRALL SA (ES) 2015-06-24 EP claimed
EP-1471919-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING 17ALPHA-FURANYLESTERS OF 17BETA-CARBOTHIOATE ANDROSTANES WITH A MUSCARINIC RECEPTOR ANTAGONIST GLAXO GROUP LTD (GB) 2005-08-10 EP claimed
EP-1200431-B1 QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTORS LIGANDS ALMIRALL PRODESFARMA AG (CH) 2003-03-26 EP claimed
US-5367043-A Durable formaldehyde-free phenolic resins, and method of preparing such resins ENZYMOL INTERNATIONAL, INC. (US) 1994-11-22 US claimed
CN-114349817-B Tubulin degrading agent based on VHL ligand and application thereof 杭州医学院 2025-02-11 CN disclosed
CN-114349657-B Azo microtubulin inhibitor and preparation method and application thereof 杭州医学院 2023-12-22 CN disclosed
CN-114349657-A Azo tubulin inhibitor and preparation method and application thereof 杭州医学院 2022-04-15 CN disclosed
CN-114349817-A VHL ligand-based tubulin degrading agent and application thereof 杭州医学院 2022-04-15 CN disclosed
CN-114349739-A Azo compound for degrading tubulin and synthesis method and application thereof 杭州医学院 2022-04-15 CN disclosed
US-11117873-B2 Oxazine compound, composition, and cured product DIC CORPORATION (JP) 2021-09-14 US disclosed
US-11117872-B2 Oxazine compound, composition and cured product DIC CORPORATION (JP) 2021-09-14 US disclosed
US-11028059-B2 Oxazine compound, composition and cured product DIC CORPORATION (JP) 2021-06-08 US disclosed
US-20020053302-A1 Epoxy resin composition for encapsulating semiconductor, and resin-encapsulated type semiconductor apparatus SUMITOMO CHEMICAL COMPANY, LIMITED 2002-05-09 US disclosed
EP-1174455-A1 Epoxy resin composition for encapsulating semiconductor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-23 EP disclosed
EP-1032559-A1 AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2000-09-06 EP disclosed
WO-1999016746-A1 AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 1999-04-08 WO disclosed
US-4595769-A Carbamate-sulfenyl-carbamoyl fluoride compounds UNION CARBIDE CORPORATION (US) 1986-06-17 US disclosed
US-4166864-A MITICIDES, INSECTICIDES UNION CARBIDE CORPORATION (US) 1979-09-04 US disclosed
US-4129601-A BIS ETHERS, PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1978-12-12 US disclosed
US-4039685-A 1-PHENOXY-2-HYDROXY-3-TERT.-BUTYLAMINO PROPANE ANTIARRHYTHMIC COMPOUNDS BOEHRINGER INGELHEIM GMBH (DT) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028059-B2 Oxazine compound, composition and cured product KDM5A, WDR5, RNF5 MAPT 147/4885GAA 2973/4885JAK2 2815/4885
US-20020053302-A1 Epoxy resin composition for encapsulating semiconductor, and resin-encapsulated type semiconductor apparatus SEM1, ABCC1, RER1 MAPT 3895/4885GAA 1666/4885JAK2 1320/4885
US-11117873-B2 Oxazine compound, composition, and cured product KDM5A, WDR5, SMC4 MAPT 150/4885GAA 2983/4885JAK2 3152/4885
US-11117872-B2 Oxazine compound, composition and cured product KDM5A, WDR5, RNF5 MAPT 148/4885GAA 3025/4885JAK2 2808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.