Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 10/20 | 0.39 |
| ▸ | THRB | P10828 | 10/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9290835 | 0.99 | THRA (0.38) | THRATHRBTSHRL3MBTL1KCNH2 | |
| SCHEMBL9855915 | 0.92 | THRB (0.37) | THRATHRB | |
| Hydrochloric Acid SCHEMBL8128505 | 0.91 | THRB (0.37) | THRATHRB | |
| SCHEMBL9855576 | 0.91 | THRA (0.42) | THRATHRB | |
| SCHEMBL8128958 | 0.91 | THRA (0.39) | THRATHRB | |
| Hydrochloric Acid SCHEMBL8120665 | 0.90 | THRA (0.41) | THRATHRB | |
| Hydrochloric Acid SCHEMBL9291092 | 0.90 | THRA (0.39) | THRATHRB | |
| SCHEMBL8151462 | 0.85 | S1PR2 (0.41) | THRATHRB | |
| SCHEMBL9856009 | 0.85 | THRA (0.37) | THRATHRB | |
| Hydrochloric Acid SCHEMBL8127558 | 0.84 | THRA (0.36) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427765-A1 | ALKOXY-4(1H)-PYRIDONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USE AS DRUGS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-05-22 | — | — | EP | disclosed |
| WO-1990001477-A1 | ALKOXY-4(1H)-PYRIDONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USE AS DRUGS | Gödecke Aktiengesellschaft (DE) | 1990-02-22 | — | — | WO | disclosed |
| EP-0354495-A1 | Alkoxy-4(1H)-pyridone derivatives, process for their preparation and their pharmaceutical use | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-02-14 | — | — | EP | disclosed |