Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674576 | 0.85 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL10811055 | 0.82 | POLB (0.40) | HPGDKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10674834 | 0.80 | GRM1 (0.44) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10679379 | 0.79 | TSHR (0.41) | KMT2AMEN1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5230905 | 0.77 | HPGD (0.56) | HPGDSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL9855344 | 0.75 | HPGD (0.47) | HPGDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL10674816 | 0.74 | SORT1 (0.43) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10652599 | 0.74 | CNR2 (0.36) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9856220 | 0.74 | HDAC8 (0.51) | SMN1; SMN2KMT2AMEN1POLBNPC1 | |
| SCHEMBL17140457 | 0.72 | KAT6A (0.47) | HPGDSMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158000-B1 | REGIO AND OPTICAL ISOMERS OF IMIDAZOLINYL TOLUIC ACIDS, ESTERS AND SALTS, THEIR METHOD OF PREPARATION AND THEIR USE AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1991-06-19 | — | — | EP | claimed |