Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27607313 | 0.84 | NOX1 (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL31657639 | 0.83 | NOX1 (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL1719765 | 0.83 | NOX1 (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL5362784 | 0.81 | NOX1 (0.52) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL293434 | 0.81 | ALOX5 (0.54) | NOX1GAAMAPTMEN1KMT2A | |
| Benzene SCHEMBL28125613 | 0.81 | ALOX5 (0.54) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL1509833 | 0.80 | NOX1 (0.50) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL7162110 | 0.80 | NOX1 (0.50) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL547518 | 0.79 | NOX1 (0.48) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL2803233 | 0.78 | GAA (0.47) | NOX1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266849-B1 | PROCESS FOR INTRODUCING A THIOCARBOXYLIC ESTER GROUP AT THE ORTHO-POSITION OF PHENOLS OR PHENYLAMINES | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4857645-A | Process for introducing a thiocarboxylic ester group at the orthoposition of phenols or phenylamines | SHIONOGI & CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0266849-A1 | Process for introducing a thiocarboxylic ester group at the ortho-position of phenols or phenylamines | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |