Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | DCLRE1B | Q9H816 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604457 | 0.86 | FOLH1 (0.57) | FOLH1DCLRE1B | |
| SCHEMBL542783 | 0.82 | PRKAB2 (0.49) | EPHX2NR1H4RARBRARARARG | |
| SCHEMBL9428167 | 0.80 | GAA (0.45) | EPHX2NR1H4 | |
| SCHEMBL506187 | 0.80 | EPHX2 (0.47) | EPHX2NR1H4RARBRARARARG | |
| SCHEMBL17049075 | 0.80 | EPHX2 (0.47) | EPHX2NR1H4RARBRARARARG | |
| SCHEMBL31490890 | 0.80 | SRD5A2 (0.57) | EPHX2NR1H4RARBRARARARG | |
| SCHEMBL13746058 | 0.80 | EPHX2 (0.47) | EPHX2NR1H4RARBRARARARG | |
| SCHEMBL669282 | 0.80 | RARB (0.54) | EPHX2NR1H4RARBRARARARG | |
| SCHEMBL2845325 | 0.80 | EPHX2 (0.47) | EPHX2NR1H4RARBRARARARG | |
| SCHEMBL23242520 | 0.79 | RARB (0.45) | EPHX2NR1H4RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |