Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 3/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | PYGM | P11217 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15450935 | 0.88 | TYMS (0.54) | POLBSMN1; SMN2TK1TYMS | |
| SCHEMBL9856150 | 0.88 | TK1 (0.55) | ABCG2ABCB1TK1 | |
| SCHEMBL4364020 | 0.86 | RNASE1 (0.48) | ABCG2ABCB1ALDH1A1POLBKMT2A | |
| SCHEMBL15492130 | 0.86 | RNASE1 (0.48) | ABCG2ABCB1ALDH1A1POLBKMT2A | |
| SCHEMBL13915248 | 0.86 | RNASE1 (0.48) | ABCG2ABCB1ALDH1A1POLBKMT2A | |
| SCHEMBL17146890 | 0.85 | TK1 (0.60) | ABCG2TK1TYMS | |
| SCHEMBL3066252 | 0.82 | SMN1; SMN2 (0.44) | ALDH1A1POLBKMT2ASMN1; SMN2TK1 | |
| SCHEMBL3085565 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1POLBKMT2ASMN1; SMN2TK1 | |
| SCHEMBL15489691 | 0.77 | RNASE1 (0.49) | ALDH1A1POLBKMT2ASMN1; SMN2TK1 | |
| SCHEMBL15489639 | 0.77 | RNASE1 (0.49) | ALDH1A1POLBKMT2ASMN1; SMN2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |