Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856122 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT | |
| SCHEMBL10793584 | 0.86 | ACACB (0.50) | ALDH1A1TSHRMAPTKMT2AACACB | |
| SCHEMBL10789195 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTKMT2AACACB | |
| SCHEMBL9856571 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL10794885 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTKMT2APTGDR | |
| SCHEMBL10394582 | 0.82 | KMT2A (0.50) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10804237 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTKMT2AACACB | |
| SCHEMBL10804244 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTKMT2AACACB | |
| SCHEMBL10805829 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTKMT2AACACB | |
| SCHEMBL5279314 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRALOX15SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |