Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789195 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TSHRACACBPLA2G4BMAPT | |
| SCHEMBL9856115 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TSHRACACBMAPTPTGDR | |
| SCHEMBL9856122 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TSHRACACBMAPTPTGDR | |
| SCHEMBL10793584 | 0.82 | ACACB (0.50) | ALDH1A1TSHRACACBMAPTLMNA | |
| SCHEMBL9856571 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRACACBMAPTKMT2A | |
| SCHEMBL10394582 | 0.78 | KMT2A (0.50) | ALDH1A1TSHRACACBRAB9ALMNA | |
| SCHEMBL10794755 | 0.76 | ACACB (0.35) | ALDH1A1TSHRACACBMAPTRAB9A | |
| SCHEMBL122883 | 0.75 | ACACB (0.45) | ACACBMAPTKMT2A | |
| SCHEMBL8082306 | 0.75 | LMNA (0.52) | ALDH1A1ACACBMAPTLMNAKMT2A | |
| SCHEMBL10804244 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRACACBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647698-A | Novel compositions | SANDOZ LTD. (US) | 1987-03-03 | — | — | US | disclosed |