Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL9855453 | 0.99 | MAOA (0.36) | MAOAMAOBCASRTRPA1CNR2 | |
| SCHEMBL8134445 | 0.77 | CYP19A1 (0.46) | CASRCNR2CYP19A1CYP17A1KDM4E | |
| SCHEMBL3064444 | 0.77 | MAPT (0.48) | MAOAMAOBTRPA1KDM4EACSL1 | |
| SCHEMBL820383 | 0.77 | TRPA1 (0.53) | MAOAMAOBTRPA1KDM4EALOX5 | |
| SCHEMBL11846005 | 0.76 | SCN1A (0.41) | MAOAMAOBTRPA1CYP19A1KDM4E | |
| SCHEMBL10423954 | 0.76 | MAPT (0.47) | MAOAMAOBTRPA1KDM4EACSL1 | |
| SCHEMBL15463348 | 0.76 | TRPA1 (0.52) | MAOAMAOBTRPA1KDM4EALOX5 | |
| Calcium SCHEMBL11450375 | 0.76 | TRPA1 (0.52) | MAOAMAOBTRPA1KDM4EALOX5 | |
| Potassium SCHEMBL3084615 | 0.76 | TRPA1 (0.52) | MAOAMAOBTRPA1KDM4EALOX5 | |
| SCHEMBL7460479 | 0.76 | TRPA1 (0.52) | MAOAMAOBTRPA1KDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981869-A | Xanthates as antitumor agents | MERZ & CO., GMBH & CO. (DE) | 1991-01-01 | — | — | US | claimed |
| US-4602037-A | USING A BISBIGUANIDE SPERMICIDE | MERZ+CO. GMBH & CO. (DE) | 1986-07-22 | — | — | US | claimed |
| US-4851435-A | CONTAINING ANIONIC ADJUVANT WITH LIPOPHILIC AND HYDROPHILIC GROUPS FOR INCREASED ACTIVITY | MERZ +CO. GMBH & CO. (DE) | 1989-07-25 | — | — | US | disclosed |