Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23295252 | 0.82 | NQO1 (0.34) | ALDH1A1KMT2AGAASMN1; SMN2NPC1 | |
| SCHEMBL10789684 | 0.79 | LTA4H (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10795235 | 0.79 | HTT (0.33) | ALDH1A1MEN1KMT2ASLC6A4CYP1A2 | |
| SCHEMBL26976737 | 0.79 | CA1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4192430 | 0.79 | CA1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9038984 | 0.78 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9621498 | 0.78 | ALDH1A1 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9344641 | 0.77 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12264121 | 0.77 | KMT2A (0.47) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL10789677 | 0.77 | PPARG (0.33) | ALDH1A1KMT2AGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4697033-A | INSECTICIDES | SANDOZ LTD. (CH) | 1987-09-29 | — | — | US | disclosed |