Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087291 | 0.92 | ALDH1A1 (0.45) | PRKCAALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL29259205 | 0.88 | MEN1 (0.50) | CYP3A4MAPTMEN1KMT2ATP53 | |
| SCHEMBL500451 | 0.88 | MEN1 (0.46) | PRKCACYP3A4MAPTUSP2LMNA | |
| SCHEMBL500452 | 0.88 | MEN1 (0.46) | PRKCACYP3A4MAPTUSP2LMNA | |
| SCHEMBL7939398 | 0.85 | PRKCA (0.46) | PRKCAALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL29094957 | 0.84 | MEN1 (0.45) | CYP3A4MAPTMEN1KMT2ATP53 | |
| SCHEMBL31538337 | 0.82 | ALDH1A1 (0.46) | PRKCAALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL31538323 | 0.82 | ALDH1A1 (0.46) | PRKCAALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL31538379 | 0.82 | ALDH1A1 (0.46) | PRKCAALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL31538307 | 0.82 | ALDH1A1 (0.46) | PRKCAALDH1A1CYP3A4MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293006-B1 | UN-NATURAL CERAMIDE RELATED COMPOUNDS AND PREPARATION THEREOF | MECT CORPORATION (JP) | 1991-06-12 | — | — | EP | claimed |