Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595856 | 1.00 | KEAP1 (0.32) | KEAP1NFE2L2HCAR2ALDH1A1TP53 | |
| SCHEMBL9856244 | 0.91 | HCAR2 (0.41) | HCAR2ALDH1A1TP53 | |
| SCHEMBL7595859 | 0.91 | HCAR2 (0.41) | HCAR2ALDH1A1TP53 | |
| SCHEMBL7719304 | 0.79 | — | — | |
| SCHEMBL9000767 | 0.75 | — | — | |
| SCHEMBL3400712 | 0.73 | HCAR2 (0.38) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL3400715 | 0.73 | HCAR2 (0.38) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL5070247 | 0.73 | HCAR2 (0.38) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL7885338 | 0.72 | KEAP1 (0.33) | KEAP1NFE2L2HCAR2ALDH1A1TP53 | |
| SCHEMBL9620593 | 0.72 | KEAP1 (0.33) | KEAP1NFE2L2HCAR2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102295560-A | Difluoroalkyl maleate and preparation method thereof | — | 2011-12-28 | — | — | CN | disclosed |
| EP-0284331-B1 | PHOTOGRAPHIC COMPOSITION CONTAINING A FLOURINATED SULFOSUCCINATE | EASTMAN KODAK COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4968599-A | COATING AIDS TO CONTROL REPELLENCIES | EASTMAN KODAK COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0284331-A1 | Photographic composition containing a flourinated sulfosuccinate | EASTMAN KODAK COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |