Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595053 | 0.78 | CTSB (0.44) | CTSBMTNR1AMTNR1BPPARGPPARA | |
| Fumaric Acid SCHEMBL9856447 | 0.74 | NOS2 (0.45) | CTSBCTSLCTSSPOLBMTNR1A | |
| Fumaric Acid SCHEMBL9856436 | 0.74 | NOS2 (0.45) | CTSBCTSLCTSSPOLBMTNR1A | |
| Fumaric Acid SCHEMBL9856450 | 0.74 | NOS2 (0.45) | CTSBCTSLCTSSPOLBMTNR1A | |
| SCHEMBL6548160 | 0.69 | ACP3 (0.46) | CTSBCTSLCTSSMTNR1AMTNR1B | |
| SCHEMBL9856887 | 0.69 | HTR2A (0.49) | CTSBCTSLCTSSMTNR1AMTNR1B | |
| SCHEMBL805204 | 0.67 | POLB (0.51) | CTSBCTSLCTSSPOLBPPARG | |
| SCHEMBL6547355 | 0.67 | ESR1 (0.46) | CTSBCTSLCTSSMTNR1AMTNR1B | |
| SCHEMBL11132299 | 0.67 | POLB (0.51) | CTSBCTSLCTSSPOLBPPARG | |
| SCHEMBL11132296 | 0.67 | POLB (0.51) | CTSBCTSLCTSSPOLBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |