Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA9 | Q16790 | 10/20 | 0.46 |
| ▸ | CA12 | O43570 | 8/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685675 | 1.00 | LMNA (0.52) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL2583271 | 1.00 | LMNA (0.52) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL11790088 | 0.92 | LMNA (0.45) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL2584864 | 0.91 | LMNA (0.44) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL10891761 | 0.91 | ALDH1A1 (0.45) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL10889211 | 0.91 | LMNA (0.45) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL10891754 | 0.91 | ALDH1A1 (0.45) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL10889208 | 0.91 | LMNA (0.45) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL31685489 | 0.89 | LMNA (0.52) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL6223971 | 0.89 | LMNA (0.41) | LMNATHRBSMN1; SMN2HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |