Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250276 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1ABCB11GSRTSHR | |
| SCHEMBL8048766 | 0.70 | PPARD (0.38) | MEN1TSHRKMT2A | |
| SCHEMBL2347991 | 0.68 | CA12 (0.32) | ALDH1A1MEN1ABCB11GSRTSHR | |
| SCHEMBL9856556 | 0.66 | ALDH1A1 (0.70) | ALDH1A1MEN1ABCB11GSRTSHR | |
| SCHEMBL9856481 | 0.66 | ALDH1A1 (0.70) | ALDH1A1MEN1ABCB11GSRTSHR | |
| SCHEMBL22616909 | 0.65 | LMNA (0.37) | ALDH1A1MEN1TSHRHTTKMT2A | |
| SCHEMBL11121024 | 0.63 | ALDH1A1 (0.38) | ALDH1A1MEN1ABCB11GSRTSHR | |
| SCHEMBL14068851 | 0.62 | ALDH1A1 (0.43) | ALDH1A1MEN1ABCB11GSRTSHR | |
| SCHEMBL14611834 | 0.61 | TSHR (0.38) | ALDH1A1TSHRHTTPMP22SMN1; SMN2 | |
| SCHEMBL10712643 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001158-A | Nitrosoureas compounds preparation thereof and utilization thereof in anticancerous | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1991-03-19 | — | — | US | disclosed |