Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849307 | 0.83 | PCNA (0.42) | MIFCA12CA1CA2CA7 | |
| SCHEMBL8155301 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1LMNAHTTACACB | |
| SCHEMBL9856510 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPK1LMNAHTTACACB | |
| SCHEMBL9621303 | 0.77 | LMNA (0.66) | SMN1; SMN2MAPK1CA12CA1CA2 | |
| SCHEMBL2481397 | 0.77 | LMNA (0.66) | SMN1; SMN2MAPK1CA12CA1CA2 | |
| SCHEMBL5789381 | 0.77 | LMNA (0.66) | SMN1; SMN2MAPK1CA12CA1CA2 | |
| SCHEMBL9836225 | 0.75 | CA12 (0.53) | SMN1; SMN2MAPK1MIFCA12CA1 | |
| SCHEMBL3404315 | 0.75 | CA12 (0.52) | SMN1; SMN2MAPK1MIFCA12CA1 | |
| SCHEMBL28081933 | 0.75 | TSHR (0.52) | SMN1; SMN2MAPK1CA12CA1CA2 | |
| SCHEMBL11428710 | 0.74 | MAPK1 (0.44) | SMN1; SMN2MAPK1MIFCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |