Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394601 | 0.82 | MTNR1A (0.46) | SMN1; SMN2LMNAKMT2AGLAHPGD | |
| SCHEMBL9856492 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1ACACBLMNAHTT | |
| SCHEMBL9856511 | 0.77 | L3MBTL1 (0.47) | SMN1; SMN2MAPK1ACACBKMT2AGLA | |
| SCHEMBL9856629 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPK1ACACBLMNAKMT2A | |
| SCHEMBL8155301 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1ACACBLMNAHTT | |
| SCHEMBL9856226 | 0.74 | MTNR1A (0.44) | SMN1; SMN2MAPK1LMNAHTTKMT2A | |
| SCHEMBL10795235 | 0.74 | HTT (0.33) | SMN1; SMN2MAPK1LMNAHTTKMT2A | |
| SCHEMBL9856588 | 0.71 | PRKAB2 (0.34) | ACACBHTTKMT2AALDH1A1MEN1 | |
| SCHEMBL10394858 | 0.71 | MTNR1A (0.48) | SMN1; SMN2LMNA | |
| SCHEMBL10800442 | 0.71 | MAPT (0.38) | SMN1; SMN2LMNAHTTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |