Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794833 | 0.83 | ACACB (0.41) | KMT2AMEN1ACACBTSHRMAPT | |
| SCHEMBL10794838 | 0.81 | ACACB (0.39) | KMT2AMEN1ACACBHRH3TSHR | |
| SCHEMBL10800531 | 0.80 | MAPT (0.41) | KMT2AACACBMAPTTDP1ALDH1A1 | |
| SCHEMBL9856638 | 0.79 | ACACB (0.45) | KMT2AMEN1ACACBTSHRMAPT | |
| SCHEMBL9856371 | 0.79 | ACACB (0.45) | KMT2AMEN1ACACBTSHRMAPT | |
| SCHEMBL9856151 | 0.79 | ACACB (0.45) | KMT2AMEN1ACACBTSHRMAPT | |
| SCHEMBL10795585 | 0.78 | KMT2A (0.41) | KMT2AMEN1ACACBHRH3TSHR | |
| SCHEMBL9856572 | 0.78 | ACACB (0.47) | ACACBHRH3TSHRMAPT | |
| SCHEMBL9856665 | 0.77 | ACACB (0.49) | ACACBHRH3TSHRKDM4EALDH1A1 | |
| SCHEMBL9856033 | 0.76 | ACACB (0.43) | KMT2AMEN1ACACBTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | claimed |
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |