Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856572 | 0.90 | ACACB (0.47) | ACACBHRH3SMN1; SMN2MAPK1TAS1R3 | |
| SCHEMBL9856638 | 0.86 | ACACB (0.45) | ACACBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL9856371 | 0.86 | ACACB (0.45) | ACACBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL9856151 | 0.86 | ACACB (0.45) | ACACBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL9856033 | 0.83 | ACACB (0.43) | ACACBSMN1; SMN2MAPK1KDM4ETAS1R3 | |
| SCHEMBL9856401 | 0.81 | L3MBTL1 (0.46) | ACACBALDH1A1HRH3SMN1; SMN2KDM4E | |
| SCHEMBL9856673 | 0.77 | MAPT (0.49) | ACACBALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL9856607 | 0.77 | ACACB (0.42) | ACACBALDH1A1HRH3SMN1; SMN2MAPK1 | |
| SCHEMBL9856531 | 0.77 | KMT2A (0.45) | ACACBALDH1A1HRH3KDM4ETSHR | |
| SCHEMBL10794790 | 0.77 | TAS1R3 (0.47) | ALDH1A1SMN1; SMN2MAPK1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |